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The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show

By: Dr. Gabrielle Lyon
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The Dr. Gabrielle Lyon Show promotes a healthy world, and in order to have a healthy world, we must have transparent conversations. This show is dedicated to such conversations as the listener; your education, understanding, strength, and health are the primary focus. The goal of this show is to provide you with a framework for navigating the health and wellness space and, most importantly, being the champion of your own life. Guests include highly trustworthy professionals that bring both the art and science of wellness aspects that are both physical and mental. Dr. Gabrielle Lyon is a Washington University fellowship-trained physician who serves the innovators, mavericks, and leaders in their fields, as well as working closely with the Special Operations Military. She is the founder of the Institute of Muscle-Centric Medicine® and serves patients worldwide.Copyright 2026 Dr. Gabrielle Lyon Biological Sciences Hygiene & Healthy Living Physical Illness & Disease Science
Episodes
  • Nobody Tells You What GLP-1s Do to Your Sex Drive | GLS #213

    Nobody Tells You What GLP-1s Do to Your Sex Drive | GLS #213
    Jun 25 2026
    The receptor that switches off your appetite on a GLP-1 drug is the same one wired into your reward circuitry, your hormones, and your blood vessels, which means when you turn down hunger, something else may be getting turned down too, and for most people taking these drugs, nobody ever checked.In this solo episode, Dr. Gabrielle Lyon discusses:Why the same drug class can improve sexual function in men with obesity while potentially dampening it in lean or postmenopausal women — and why the deciding factor isn't the drug, it's the bodyHow rapid weight loss raises SHBG, the protein that soaks up free testosterone, so a "normal" total testosterone result can hide a real deficit your bloodwork won't flagWhy women make up 60–70% of GLP-1 prescriptions yet the entire evidence base for female sexual function is two case reports, with zero validated questionnaires in any pivotal trialThe three-tier action plan for anyone on or about to start a GLP-1 — baseline your sexual function first, get free testosterone tested, and protect muscle with protein and resistance trainingWhether you're on a GLP-1 drug or considering one, you'll walk away knowing exactly what to measure before you start and what to watch for after — so a change in your sexual health gets caught as the vital sign it is, instead of being quietly dismissed.Thank you to our sponsors:Cozy Earth - Go to https://bit.ly/44qcXtu for up to 20% off! Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/3QEpYMX or find yours in store at https://bit.ly/3SGAEv3 .Kettle & Fire - Head to https://bit.ly/4oJokGu and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction01:30 - The 35-year-old patient case04:00 - The question: harm or help?05:00 - The case against: the 4.5x ED study06:30 - FAERS database and 182 reports08:00 - Reward circuits, blood flow, and SHBG11:00 - Women are 70%, the data is two case reports12:30 - The case for: detection bias explained15:00 - Validated studies show testosterone rising17:00 - GLP-1 vs testosterone therapy and fertility19:00 - Same receptor, different body22:00 - Cross-examination: holes in both sides26:00 - Why the drugs may not all be the same30:00 - Confidence levels: what Lyon actually believes33:00 - Tier 1: baseline, hormones, protein, training35:00 - Tier 2 and 3: dose, molecule switch, adjuncts36:30 - Your sexuality is a vital sign If you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
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    38 mins
  • Why Strength Beats Cardio After 50: Muscle, Longevity & Bone Density - Lisa Smith-Batchen

    Why Strength Beats Cardio After 50: Muscle, Longevity & Bone Density - Lisa Smith-Batchen
    Jun 23 2026
    You might think more cardio is the key to aging well but Lisa Smith-Batchen, who has run 135 miles through Death Valley ten times, says it's strength that actually carries you through the decades.In this episode, Dr. Gabrielle Lyon sits down with Lisa Smith-Batchen, one of the most decorated ultra-endurance athletes in American history and a 10-time Badwater 135 finisher, to discuss:Why being strong matters more than being fast and why "it's not the running that helps me run, it's being strong"The first movement everyone should train at any age: sit to stand, followed by squats, wall sits, lunges, and pushupsWhy cutting protein after 60 backfires, and why Lisa fuels on roughly 80% protein calories during racesHow to start lifting late, her 85-year-old client went from 5-pound weights to 230-pound farmer carriesThe fall that ended her father's life, and why "pick your feet up" became her mission for aging athletesYou'll walk away with a clear, muscle-first blueprint for staying strong, mobile, and independent for life — and the motivation to start today instead of waiting for another Monday.Thank you to our sponsors:Cozy Earth - Go to https://bit.ly/44qcXtu for up to 20% off!Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/3QEpYMX or find yours in store at https://bit.ly/3SGAEv3 .Kettle & Fire - Head to https://bit.ly/4oJokGu and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Lisa Smith-Batchen at:Website: https://dreamchaserevents.com/Instagram: https://www.instagram.com/coachlisasmithbatchenFacebook: https://www.facebook.com/lisa.smithbatchenConnect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction02:10 - From marathon to the Badwater 13505:31 - The first race and learning the hard way06:41 - Inside the pain cave13:46 - Why she went back ten times16:51 - Bonking, hydration, and what changed21:12 - Finding your why28:04 - Running for something greater33:25 - Strong over fast: the real secret35:59 - The lifting myths men and women believe44:13 - Where a beginner should start47:02 - Sit to stand: the non-negotiable move48:56 - The habit that killed her father51:11 - Why falls are so devastating54:14 - The danger of low-protein advice for older adults59:00 - Stop waiting for Monday01:01:37 - Fueling: protein, sodium, and calories per hour01:13:01 - Why a DNF isn't failure01:18:13 - Unfinished business and the right choiceIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
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    1 hr and 23 mins
  • Laura Horvath, Chris Hinshaw & James Sprague: What Separates Champions From Everyone Else

    Laura Horvath, Chris Hinshaw & James Sprague: What Separates Champions From Everyone Else
    Jun 18 2026

    What does it actually mean to win at the highest level? In this powerful compilation, I’m with 2024 CrossFit Games champion James Sprague, 2023 CrossFit Games champion Laura Horvath, and legendary endurance coach Chris Hinshaw to unpack the mental game behind elite performance, the vulnerability that follows victory, and why champions are often more fragile in the moments just after they win. What does winning mean to you right now?

    Connect with James Sprague

    Website: https://games.crossfit.com/athlete/900251

    YouTube: https://youtube.com/@spraguerrrr?si=zTrH9d5valcjlq-t

    Instagram: https://www.instagram.com/spraguerrrr/

    Facebook: https://www.facebook.com/spraguerrrr/

    Connect with Laura Horvath

    Website: https://games.crossfit.com/athlete/591912

    YouTube: https://youtube.com/@kaduzs23?si=3j8mXAnf38H7uGvi

    Instagram: https://www.instagram.com/laurahorvaht/?hl=en

    Facebook: https://www.facebook.com/laurhorvath/

    TikTok: https://www.tiktok.com/@laurahorvaht

    X: https://x.com/laurahorvaht

    Connect with Chris Hinshaw

    Website: https://www.aerobiccapacity.com/

    Instagram: https://www.instagram.com/hinshaw363/

    Facebook: https://www.facebook.com/hinshaw363/

    Thank you to our sponsors:

    Bodyhealth - Use the code “LYON20” to get 20% off your first order! https://bit.ly/4r2ImeF

    Our Place - Use code “DRLYON” for 10% of sitewide. https://bit.ly/4r77SiU

    Manukora - save 31% plus $25 worth of free gifts. https://bit.ly/4sglER1

    Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

    YouTube: https://bit.ly/4boCFC3

    Spotify: https://bit.ly/4cWTbLG

    Connect with Dr. Gabrielle Lyon:

    Instagram: https://www.instagram.com/drgabriellelyon/

    TikTok: https://www.tiktok.com/@drgabriellelyon

    X (Twitter): https://x.com/drgabriellelyon

    Facebook: https://www.facebook.com/doctorgabriellelyon

    Timestamps:

    00:00 - Intro of Show

    00:52 - The Rogue Invitational and qualifying

    01:41 - Applying friction in elite training

    02:27 - Why winners are vulnerable

    02:47 - CrossFit and HYROX recovery demands

    03:23 - Active versus passive rest

    04:14 - Why records keep breaking

    05:18 - Training by feel without wearables

    06:16 - Mastering movement before intensity

    07:21 - Reframing pain as growth

    08:25 - How CrossFit events are structured

    09:47 - Building structural integrity

    10:38 - The three bases of the sport

    11:34 - Getting comfortable being uncomfortable

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.
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    13 mins
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